糖苷混合物FAB质谱分析技术的研究

我们曾阐明了糖苷单-化合物分子量的简明, 快速确定方法, 根据糖苷化合物中引入碱金属离子的FAB正离子的加合离子峰而难于找到碎片的加合离子峰, 现在我们在糖苷混合物中, 同时引入两种碱金属离子Na^+和Li(两元素原子量之差为16), 由此得到的糖苷混合物的FAB正离子谱中, 就出现两个一组的多组强峰, 且每组的两峰之质量差为16, 每组中低质量峰为M+Li]^+峰, 高质量为M+Li]^+峰, 根据两峰已标出的质量数便可轻易地定出各成分的分子量来。谱图中出现的强峰组数就是糖苷混合物的成分数。

The study of alkali metal adduct lons technique of mixture of glycosides in fast atom bombardment mass spectrometry

We explained a simple method of determining the molecuar weigh of a pure glycolside. the method was based on the law that when glycosides were mixed with alali metal ions only the adduct lons of molecule with alkali metal ions appeard in the high mass region of their fast atom bombardmetn mass spectra.in the same way when a mixture of glycosides was mixed with an appropriate amount of Na+ and Li+ pairs of strong peaks appeared in the FAB mass spectra. these adduct ions were easily recognized due to fact that they were very strong and their mass difference was uniue(16u). from these adducts ions, the molecular weitht of each glycoside inthe mixture may be determined. this technique has not been reported previously.