New Guaiane Sesquiterpenes from the Fruits of Torilis japonica |
| |
| Authors: | Lee In-Kyoung Lee Jeong-Hyung Hwang Eui Il Yun Bong-Sik |
| |
| Affiliation: | Division of Biotechnology, College of Environmental and Bioresources Sciences, Chonbuk National University, Jeonju, Korea. |
| |
| Abstract: | Three new guaiane type sesquiterpenes were isolated from the methanolic extract of the fruits of Torilis japonica together with a known compound, torilin (1). Their structures were established as 11-acetoxy-8-isobutyryl-4-guaien-3-one (2), 11-acetoxy-8-methacrylyl-4-guaien-3-one (3), and 11-acetoxy-8-propionyl-4-guaien-3-one (4) by spectroscopic methods. These compounds inhibited lipopolysaccharide (LPS)-induced nitric oxide production in murine macrophages RAW 264.7 cells. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
