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Recent Progress on Graphene‐based Electrochemical Biosensors
Authors:Yu Zhang  Jingjing Shen  Huihua Li  Linlin Wang  Dashun Cao  Xiaomiao Feng  Yuge Liu  Yanwen Ma  Lianhui Wang
Affiliation:1. Key Laboratory for Organic Electronics and Information Displays and Institute of Advanced Materials, National Jiangsu Synergistic Innovation Center for Advanced Materials (SICAM), Nanjing, P. R. China;2. The South Subtropical Crops Research Institute Chinese Academy of Tropical Agricultural Science, Zhanjiang, P. R. China
Abstract:The detailed records and conclusions on the important advancements in graphene‐based electrochemical biosensors have been reviewed. Due to their outstanding properties, graphene‐based materials have been widely studied for the accurate electrochemical detection of many biomolecules, which is extremely vital to the development of biomedical instruments, clinical diagnosis, and disease treatment. This review discusses the graphene research for the effective immobilization of enzymes, including glucose oxidase, horseradish peroxidase, and hemoglobin, etc., and the accurate detection of biomolecules, including glucose, hydrogen peroxide, dopamine, ascorbic acid, uric acid, nicotinamide adenine dinucleotide, DNA, RNA, and carcinoembryonic antigen, etc. In most of the cases, the graphene‐based biosensors exhibited remarkable performance with high sensitivities, wide linear detection ranges, low detection limits, and long‐term stabilities.
Keywords:biosensors  electrochemical biosensors  enzymatic  graphene  nonenzymatic
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