Analysis of therapeutic effectiveness attained through generation of three alpha particles in proton-boron fusion reaction based on Monte Carlo simulation code |
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Authors: | Sunmi Kim Do-Kun Yoon Han-Back Shin Moo-Sub Kim Tae Suk Suh |
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Institution: | 1.Department of Biomedical Engineering, Research Institute of Biomedical Engineering, College of Medicine,The Catholic University of Korea,Seoul,Korea |
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Abstract: | This study analyzed the effectiveness attained through generation of three alpha particles in proton-boron fusion therapy (PBFT) based on a Monte Carlo simulation. PBFT is based on a fusion reaction between protons and boron. Three alpha particles are emitted from this reaction. The three alpha particles cause greater damage to tumor cells than the single alpha particle produced in the boron neutron capture reaction or conventional therapy. In addition, the intrinsic proton dose pattern follows Bragg-peak curve. We confirmed an energy deposition by the alpha particle and verified the therapeutic effect of the PBFT. |
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