Recording force events of single quantum-dot endocytosis |
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Authors: | Shan Yuping Hao Xian Shang Xin Cai Mingjun Jiang Junguang Tang Zhiyong Wang Hongda |
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Institution: | State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, PR China. |
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Abstract: | We applied force spectroscopy based on atomic force microscope (AFM) to demonstrate the possibility of measuring the interaction force between single quantum-dots (QDs) and living cells at single particle level under native conditions. In the force-distance cycle, we recorded the events of cellular uptake of single QDs and single QD detachment from the cell. |
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