Sequential Birch reaction and asymmetric Ir-catalyzed hydrogenation as a route to chiral building blocks |
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Authors: | Paptchikhine Alexander Itto Kaori Andersson Pher G |
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Affiliation: | Department of Biochemistry and Organic Chemistry, Uppsala University, Box 576, S-75123 Uppsala, Sweden. |
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Abstract: | A range of 1,2,4-trisubstituted cyclohexadienes obtained from the Birch reaction were hydrogenated asymmetrically to produce synthetically valuable chiral compounds in high enantio- and diastereoselectivity. |
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