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Nanostructuring carbon fibre probes for use in central venous catheters |
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| Authors: | Meixian Li Jolene Phair Marco F. Cardosi James Davis |
| Affiliation: | 1. College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China;2. School of Engineering, University of Ulster, Jordanstown, Northern Ireland BT37 0QB, UK;3. Lifescan Scotland Ltd, Beechwood Park North, Inverness IV2 3ED, UK |
| Abstract: | A carbon fibre probe is described which utilises the oxidation of an endogenous biomarker to provide diagnostic information on the condition of intravascular access lines. The probe surface was modified through anodic oxidation to provide a high selectivity towards urate which was used as a redox probe through which the pH could be determined. A Nernstian response (−60 mV/pH) was obtained which was free from the interference of other redox species common to biofluids. The electroanalytical performance of the probe has been optimised and the applicability of the approach demonstrated through testing the responses in whole blood. |
| Keywords: | Carbon fibre Catheter pH Uric acid Biofilm Infection |
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