Imaging of subcutaneous blood vessels and flow velocity profiles by optical coherence tomography |
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Authors: | M Bonesi S G Proskurin and I V Meglinski |
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Institution: | (1) Laser Biomedical Applications & Instrumentation Division, Raja Ramanna Centre for Advanced Technology, Indore, 452013, India; |
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Abstract: | We have applied a compact low power rapid scanning Doppler Optical Coherence Tomography system to monitor multi-dimensional
velocity profiles within the complex vessels and simultaneous real-time non-invasive imaging of skin tissues morphology in
vivo, in the wavelength range of 1.3–1.5 nm. Optical clearing of skin tissues has been utilized to achieve depth of OCT images
up to 1.7 mm. Current approach enables applying low-power (0.4–0.5 mW) and low-noise broadband near-infrared light sources
and obtaining OCT images with down to 12 μm spatial resolution. Two-dimensional time-domain OCT images of complex flow velocity
profiles in blood vessel phantom and in vivo subcutaneous human skin tissues are presented. The effect of optical clearing
on in vivo images is demonstrated and discussed. |
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Keywords: | |
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