FTIR studies of vitamin E-cholesterol-DPPC membrane interactions in CH2 region |
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| Authors: | Feride Severcan Ülkü Baykal ? Süzer |
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| Institution: | Department of Biological Sciences, Middle East Technical University, 06531, Ankara, Turkey. |
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| Abstract: | Binary and ternary mixtures of alpha-tocopherol (alphaT), cholesterol and dipalmitoyl phosphatidylcholine (DPPC) in the form of multilamellar liposomes have been investigated by Fourier Transform Infrared Spectroscopy (FTIR). Investigation of frequencies, bandwidths and band shapes of CH(2) stretching and scissoring bands indicate that the effect of alphaT is dominant in comparison with cholesterol and alphaT decreases the interaction of cholesterol with phospholipid membranes. |
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