Estimating optical properties in layered tissues by use of the Born approximation of the radiative transport equation |
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Authors: | Kim Arnold D Hayakawa Carole Venugopalan Vasan |
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Institution: | School of Natural Science, University of California, Merced, P.O. Box 2039, Merced, California 95344, USA. adkim@ucmerced.edu |
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Abstract: | We use the Born approximation of the radiative transport equation to recover simultaneously the absorption and scattering coefficients in a single layer of a two-layer tissue sample from reflectance data. This method reduces the estimation of both optical properties to a single linear, least-squares problem. It is valid over length scales smaller than a transport mean free path and hence is useful for epithelial tissue layers. We demonstrate the accuracy of this method by using spatially resolved reflectance data computed with Monte Carlo simulations. |
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