Dye-doped silica nanoparticles as efficient labels for glycans |
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| Authors: | Wang Xin Ramström Olof Yan Mingdi |
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| Affiliation: | Department of Chemistry, Portland State University, P.O. Box 751, Portland, Oregon 97207-0751, USA. |
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| Abstract: | We report that dye-doped fluorescent silica nanoparticles (FSNPs) are highly efficient labels for glycans. Mono- and oligo-saccharides were conjugated to FSNPs using a general photocoupling chemistry. FSNP-labeled glycans were applied to image and detect bacteria, and to study carbohydrate-lectin interactions on a lectin microarray. |
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