Abstract: | Products from the anionic arylation of acrylonitrile show ring closure on interaction with S,N-nucleophiles. The reactions of 3-aryl-2-halopropionitriles with thiourea and ammonium N-phenyldithiocarbamate give respectively 2,4-diimino-5-arylmethylthiazolidines and 4-amino-5-arylmethyl-3-phenyl-4-thiazolin-2-thiones. Hydrogen bromide reacts with 3-aryl-2-thiocyanatopropionitriles to give 4-amino-5-arylmethyl-2-bromothiazoles.See [1] for Part 3.Ivan Franko L'vov State University, L'vov 2906602, Ukraine. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 97–100, January, 1999. |