Natural and edible biopolymer poly-gamma-glutamic acid: synthesis, production, and applications |
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| Authors: | Sung Moon-Hee Park Chung Kim Chul-Joong Poo Haryoung Soda Kenji Ashiuchi Makoto |
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| Institution: | Department of Bio & Nanochemistry, Kookmin University, 861-1 Chongnung-dong, Songbuk-gu, Seoul 136-702, Korea. smoonhee@kookmin.ac.kr |
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| Abstract: | Poly-gamma-glutamic acid (gamma-PGA) is a very promising biodegradable polymer that is produced by Bacillus subtilis. Gamma-PGA is water-soluble, anionic, biodegradable, and edible. This paper reviews the production of a strain of gamma-PGA and recent developments with respect to applications in terms of Ca absorption, moisturizing properties, gamma-PGA conjugation, super absorbent polymer, and so on. Our recent research shows that gamma-PGA can be used as an immune-stimulating and anti-tumor agent, especially at high molecular weight. |
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| Keywords: | Bacillus subtilis (chungkookjang) poly‐γ‐glutamic acid high molecular weight immune‐stimulating agent anti‐tumor agent |
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