Two-dimensional Fourier transform ion cyclotron resonance mass spectrometry: reduction of scintillation noise using Cadzow data processing |
| |
| Authors: | van Agthoven Maria A Coutouly Marie-Aude Rolando Christian Delsuc Marc-André |
| |
| Affiliation: | Miniaturisation pour la Synthèse l'Analyse et la Protéomique, USR CNRS 3290, Institut Michel-Eugène Chevreul, FR CNRS 2638 and Protéomique, Modifications Post-Traductionnelles et Glycobiologie, IFR 147 Université de Lille 1, Sciences et Technologie, 59655 Villeneuve d'Ascq cedex, France. marie.van‐agthoven@univ‐lille1.fr |
| |
| Abstract: | In two-dimensional Fourier transform ion cyclotron resonance mass spectrometry (2D FTICR-MS), scintillation noise, caused mostly by fluctuations in the number of ions in the ICR cell, is the leading cause for errors in spectrum interpretation. In this study, we adapted an algorithm based on singular value decomposition and first introduced by Cadzow et al. (IEE Proceedings Pt. F 1987, 134, 69) to 2D FTICR-MS and we measured its performance in terms of noise reduction without losing signal information in the 2D mass spectrum. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
