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Total asymmetric synthesis of sperabillins B and D
Authors:Davies Stephen G  Kelly Richard J  Mortimer Anne J Price
Institution:Dyson Perrins Laboratory, University of Oxford, South Parks Road, Oxford, UK OX1 3QY. steve.davies@chemistry.ox.ac.uk
Abstract:A concise route to the core fragment of sperabillins B and D, methyl (3R,5R,6R)-3,6-diamino-5-hydroxyheptanoate, has been developed with a subsequent novel protection strategy allowing the total asymmetric synthesis of sperabillins B and D.
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