The Synthesis of Novel Iodinated Iminodiacetic Acid Analogues as Hepatobiliary Imaging Agents |
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| Authors: | Email author" target="_blank">Jasmina S?Brbori?Email author Sote?Vladimirov Mirjana S?Jovanovi? Nikola?Dogovi? |
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| Institution: | (1) Institute of Pharmaceutical Chemistry and Drug Analysis, Faculty of Pharmacy, Belgrade, Serbia and Montenegro;(2) Vin a Institute of Nuclear Sciences, Laboratory for Radioisotopes, Belgrade, Serbia and Montenegro;(3) Military Technical Institute, Belgrade, Serbia and Montenegro |
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| Abstract: | Summary. The synthesis and characterization of N-2-4-iodo-2,6-bis(1-methylethyl)phenyl]amino]-2-oxoethyl]-N-(carboxymethyl)glycine and N-2-(4-iodo-2,6-diethylphenyl)amino]-2-oxoethyl]-N-(carboxymethyl)glycine is presented, as well as a modified and improved synthesis of N-2-(2,4-diiodo-6-methylphenyl)amino]-2-oxoethyl]-N-(carboxymethyl)glycine. These compounds are new agents for hepatobiliary imaging. |
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| Keywords: | , IDA analogues, Halogenation, NMR spectroscopy, IR spectroscopy, Mass spectroscopy, |
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