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Straightforward copper-catalyzed synthesis of pyrrolopyrazoles from halogenated pyrazolecarbaldehydes
Authors:Maloy NayakHarikrishna Batchu  Sanjay Batra
Institution:Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, PO Box 173, Lucknow 226001, UP, India
Abstract:Straightforward synthesis of a variety of pyrrolo-fused pyrazoles via a cascade reaction between halopyrazolecarbaldehydes and ethylisocyanoacetate in the presence of copper and a base is described.
Keywords:Pyrazole  Pyrrole  Copper  Cascade  Cross-coupling
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