Synthesis of 3'-aroyl-4'-hydroxyspiro-[indole-3,2'-furan]-2,5'(1H)-diones |
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Authors: | V. L. Gein E. B. Levandovskaya V. N. Vichegjanina |
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Affiliation: | (1) Perm State Pharmaceutical Academy, Perm, 614990, Russia |
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Abstract: | It was found that adducts of 3'-aroyl-4'-hydroxyspiro[indole-3,2'-furan]-2,5'(1H)-diones with tetramethylguanidine are formed when equimolar amounts of methyl aroylpyruvates, isatin, and N,N,N',N'-tetramethylguanidine are heated briefly in dioxane. |
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