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Determination of myocardial ischemia and degree of reperfusion based on optical coherence tomography |
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| Authors: | Haiyu Chen Guoxing Weng Zhifang Li Hui Li Xiamei Cai |
| Affiliation: | Haiyu Chen 1,Guoxing Weng 1,Zhifang Li 2,Hui Li 2,and Xiamei Cai2 1Department of Cardiovascular Surgery,Fujian Provincial Hospital,Fujian Medical University,Fuzhou 350001,China 2Key Laboratory of Optoelectronic Science and Technology for Medicine,School of Physics and OptoElectronics Technology,Fujian Normal University,China |
| Abstract: | The feasibility of applying optical coherence tomography (OCT) in determining the degree of myocardial ischemia-reperfusion injury is assessed. The left anterior descending coronary artery of 90 Sprague-Dawley rats are ligated and reperfused at different times. The total attenuation coefficient obtained from the OCT images in the experimental group keeps increasing with reperfusion time and highly correlates with the histopathological characteristics (P < 0.01). We present evidence proving the feasibility o... |
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