Synthesis and Biological Activities of O-Alkyl,O-Aryl,O-{Z-[1-Phenyl-2-(1H-1,2,4-triazol-1-yl)ethylidene]amino} Phosphorothioates |
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Authors: | Liu Meng De-Qing Shi |
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Institution: | 1. Key Laboratory of Pesticide &2. Chemical Biology of Ministry of Education, College of Chemistry , Central China Normal University , Wuhan, Hubei, P. R. China |
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Abstract: | A series of title compounds 2 were efficiently synthesized via the condensation of 1-phenyl-2-(1H-1,2,4-triazol-1-yl)ethanone oxime with various asymmetric thiophosphoryl chlorides in sodium hydroxide powder and acetonitrile system. The structures of title compounds 2 were confirmed by IR, 1H NMR, 31P NMR, EI-MS, and elemental analysis. The results of preliminary bioassays indicated that the title compounds 2 possessed good to moderate insecticidal activity against aphides at the dosage of 250 mg/L, and some of them exhibited moderate fungicidal activities at the concentration of 100 mg/L. |
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Keywords: | Biological activity 1-phenyl-2-(1H-1 2 4-triazol-1-yl)ethanone oxime phosphorothioate |
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