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ONE-POT SYNTHESIS OF N-ALKYL SUBSTITUTED PHOSPHORYL GUANIDINES |
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| Authors: | Marcos Costa Souza William Pires Macedo Marcelo Campos M Silva Guilherme Costa de O Ramos Helmut G Alt |
| Institution: | 1. Universidade Federal Fluminense , Rio de Janeiro, Brazil;2. Universit?t Bayreuth , Bayreuth, Germany |
| Abstract: | This article describes an attractive and one-pot synthesis of the title compound by phosphorylation of just prepared N-substituted guanidines from cyanamide and the desired amine. The method allows a variety of N-substituents to hang on the final phosphoryl guanidine as a function of the wider availability of commercial simple amines. |
| Keywords: | N-alkyl guanidines phosphoramidic acid phosphoryl guanidines |