One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones and Their Sulfur Derivatives with H2SO4 Supported on Silica Gel or Alumina |
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Authors: | Karim Akbari Dilmaghani Behzad Zeynizadeh Mahdi Yari |
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Institution: | Department of Chemistry, Faculty of Sciences , Urmia University , Urmia, Iran |
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Abstract: | The one-pot condensation of aromatic aldehydes, β-dicarbonyl compounds, and urea or thiourea in the presence of H2SO4 supported on silica gel or alumina (80% m/m) in refluxing n-hexane produces 3,4-dihydropyrimidin-2(1H)-ones and their sulfur derivatives in high to excellent yields. |
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Keywords: | Alumina Biginelli reaction 3 4-dihydropyrimidin-2(1H)-one H2SO4 silica gel |
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