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Novel Synthesis of Oxygenated Coumarins from Substituted Phenols Mediated by Vinyl Triphenylphosphonium Salt Under Microwave Irradiation |
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| Authors: | Rahim Hekmatshoar Sanaz Souri Mahshid Rahimifard Farnoosh Faridbod |
| Affiliation: | Azzahra University , Vanak, Tehran, Iran |
| Abstract: | Protonation of the highly reactive 1:1 intermediates produced in the reaction between triphenylphosphine and dimethyl acetylenedicarboxylate(DMAD) by substituted phenols lead to vinyl triphenylphosphonium salts, which undergo aromatic electrophilic substitution reaction with a phenolate conjugate base to produce 4-carboxymethyl coumarins in fairly highly yields. |
| Keywords: | 4-Carboxymethyl Coumarins Dimethyl Acetylenedicarboxylate(DMAD) Phenols Triphenylphosphine Vinyl Triphenyl Phosphonium Salts |