SYNTHESIS,NMR AND MOLECULAR MODELING STUDY OF 4,9a-DIARYL-9,9a-DIHYDRO 1H-[1,4]THIAZINO[4,3-a][1,3]BENZIMIDAZOLES |
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| Authors: | E. Karthikeyan S. Perumal S. Selvaraj |
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| Affiliation: | Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University , Madurai, India |
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| Abstract: | A series of substituted 4,9a-diaryl-9,9a-dihydro-1H-[1,4]thiazino[4,3-a][1,3]benzimidazoles was prepared in good yields from the reaction of bis(aroylmethyl) sulfides with ortho-phenylenediamine in glacial acetic acid under reflux and under microwave irradiation. Microwave irradiation is found to accelerate the reaction, besides giving better yield in the case of the thiazinobenzimidazoles with electron-withdrawing groups in the aryl rings than the thermal reaction. |
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| Keywords: | 1H NMR 13C NMR benzimidazole microwave irradiation thiazine |
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