SYNTHESIS OF PYRIDAZOTHIENOTHIAZINE AND PYRIMIDOTHIENOPYRIDAZINES |
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| Authors: | Sh M Radwan A M Kamal El-Dean |
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| Institution: | Chemistry Department, Faculty of Science , Assiut University , Assiut, 71516, Egypt |
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| Abstract: | Abstract 3-amino-4,5-diphenylthieno2,3-c]pyridazine-2-arylcarboxamide 2 underwent cyclization with triethyl orthoformate and with nitrous acid to give the pyrimidothienopyridazines 3a-c, 4b respectively. 3-amino-4,5-diphenylthieno2,3-c] pyridazine-2-carbohydrazide 6 reacted with aromatic aldehydes to give the corresponding carbohydrazones 7a-c. Compound 7 reacts with triethyl orthoformate, acetic anhydride or with CS2/pyridine to produce pyrimidothienopyridazines 8,9 and pyridazothienothiazine 11. |
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| Keywords: | Thienopyridazines Pyrimidothienopyridazanies Pyridazothienothiazines |
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