1,4-Diazepines Bearing Thieno(2,3-b)Thiophene and Cyclohexene Carboxylate Moieties |
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| Authors: | Ahmed M M El-Saghier Mansour A Makhlouf Mahmoud F Farhat |
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| Institution: | 1. Chemistry Department , South Valley University , Sohag, Egypt;2. Chemistry Department , Al-Fateh University , Tripoli, Libya |
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| Abstract: | Bisthieno(3,2-b)-1,4-diazepine] (4) and bisimidazo(1′,2′)thieno(3,2-b)-1,4-diazepine (7) derivatives were prepared starting with thieno(2,3-b)thiophenes (1) and (2), respectively. Also, benzodiazepine derivatives (11a–f) were prepared via a reaction of cyclohexenone carboxylates (8a–f) with cyclohexylamine and chloroacetyl chloride followed by cyclization. Also, dibenzoazepines (13) and (14a,b) were prepared via a reaction of (8a) with o-phenylenediamine and o-aminophenol or o-aminothiophenol. |
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| Keywords: | 1 4-Diazepine imidazothieno-1 4-diazepines thienodiazepine thienothiophene |
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