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Antimony Trichloride Catalyzed Condensation of Indole and Carbonyl Compounds: Synthesis of Bis(indolyl)methanes
Authors:A Srinivasa  Belakatta P Nandeshwarappa  Balaji M Kiran  Kittappa M Mahadevan
Institution:Chemical Sciences , Kuvempu University , Shankaraghatta , Karnataka , India
Abstract:A mild and efficient condensation reaction of indoles with various aldehydes and ketones under catalysis of antimony trichloride (SbCl3) afforded biologically important bis(indolyl)methanes in good yield. The structures of all the newly synthesized compounds were elucidated on the basis of IR, 1H NMR and mass spectral data.
Keywords:Aldehydes  antimony trichloride  ketones  bis(indolyl)methanes  indoles
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