Synthesis and Tautomeric Structure of 7-Arylhydrazono-7H-[1,2,4]Triazolo[3,4-b][1,3,4]Thiadiazines |
| |
Authors: | Mosselhi A N Mosselhi Magda A Abdallah Yassin F Mohamed Ahmad S Shawali |
| |
Institution: | Department of Chemistry, Faculty of Science , University of Cairo , Giza , Egypt |
| |
Abstract: | Two synthetic approaches were developed for the title compounds 8a-g via coupling of diazotized anilines with 7-acetyl-6-methyl-3-phenyl-7H-1,2,4]triazolo3,4-b]1,3,4]thiadiazine 7 , and reaction of N-aryl 2-oxopropanehydrazonoyl chlorides 9 with 4-amino-3-mercapto-5-phenyl-1,2,4-triazole 1 . The tautomeric structures of 8 were elucidated by their spectral analyses and correlation of their acid dissociation constants with Hammett equation. |
| |
Keywords: | 1 2 4-triazole-3-thione [1 2 4]triazolo[3 4-b][1 3 4]thiadiazines Hydrazonoyl Halides Tautomerism Thiohydrazonates |
|
|