Unexpected Reactivity of Ethyl 2-(Diethylphosphono)Propionate Toward 2,2-Disubstituted-1,3-cyclopentanediones |
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| Authors: | R Aav T Kanger T Pehk M Lopp |
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| Institution: | 1. Department of Chemistry, Faculty of Science, Tallinn University of Technology, Estonia;2. National Institute of Chemical Physics and Biophysics, Estonia |
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| Abstract: | Abstract A Horner-Wadsworth-Emmons reagent-ethyl 2-(diethylphosphono)propionate in the reaction with 2,2-disubstituted-1,3-cyclopentanediones, results in 4-oxohexanoic acid ethyl ester derivative up to 90% isolated yield. 31P-13C- and 1H-NMR study of the intermediates of the reaction involving the ethyl 2-(diethylphosphono)propionate was accomplished. |
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| Keywords: | Keywords 2 2-Disubstituted-cyclopentanedione 31P-13C- and 1H-NMR-study γ - ketoester phosphoryl-stabilized carbanion retro-aldol cleavage |
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