2-Amino-4-dimethylamino-1-thia-3-azabutadienes as Precursors of Thiazoles |
| |
| Authors: | C. Landreau D. Deniaud A. Reliquet J. C. Meslin |
| |
| Affiliation: | Faculté des Sciences et des Techniques , Laboratoire de Synthèse Organique , France |
| |
| Abstract: | The reaction of 2-amino-4-dimethylamino-1-thia-3-azabutadienes 1 with f -bromoketones gave rise to 2-aminothiazoles 2 together with 2-( N , N -dimethylaminomethylenamino)thiazoles 3 . Competitive mechanisms are described. Furthermore, reaction of diene 1a with methyl f -bromoacetate or hydroxylamine- O -sulfonic acid yielded respectively 2-( N , N -dimethylaminomethylenamino)thiazolin-4-one 4 and 5-amino-1,2,4-thiadiazole 5 . |
| |
| Keywords: | 2,4-Diamino-1-thia-3-azabutadienes 1,2,4-thiadiazole Thiazoles Thiazolin-4-one |
|
|
