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One-Pot Three-Component Synthesis of β -Acylaminoketones Containing a Thiophene Ring by the Use of Tetrachlorosilane-Zinc Chloride as a Binary Reagent Under Ambient Conditions
Authors:Doria S Badawy  Ebrahim Abdel-Galil  E M Kandeel  Wahid M Basyouni  Khairy A M El-Bayouki  Tamer K Khatab
Institution:1. Chemistry Department, Faculty of Science , Mansoura University , Mansoura , Egypt;2. Organometallic and Organometalloid Chemistry Department, National Research Centre , Dokki , Cairo , Egypt
Abstract:A new route for the synthesis of β -acylaminoketones containing a thiophene ring through multicomponent condensation reaction of different ketones, different aldehydes, and different nitriles with tetrachlorosilane (TCS) and zinc chloride as the binary reagent is described.
Keywords:β-Acylaminoketones  binary reagent  tetrachlorosilane  thiophene
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