Antitumor Activity of Some Novel 1,2,5-Thiadiazole Derivatives |
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| Authors: | Z. H. Ismail M. M. Ghorab E. M. A. Mohamed H. M. Aly M. S. A. El-Gaby |
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| Affiliation: | 1. Department of Chemistry, Faculty of Science(Girls) , Al-Azhar University , Cairo, Egypt;2. Department of Drug Radiation Research , National Center for Radiation Research and Technology , Nasr City, Cairo, Egypt;3. Department of Chemistry, Faculty of Science , Al-Azhar University at Assiut , Assiut, Egypt |
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| Abstract: | Some novel thiourea,1,2,4-triazole, quinazoline, thieno[2,3-d]pyrimi-dine, and thiazolidine derivatives were synthesized to evaluate their antitumor activity. Compound (3f) is nearly as active as reference drug, (Doxorubicin) as positive control. |
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| Keywords: | 1,2,5-Thiadiazole antitumor activity pyrazole quinazoline derivatives thiourea |
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