Sulfur-Bonded Coordination Compounds of Palladium(II) and Platinum(II) and Their Antimicrobial Activity |
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Authors: | Krishna Sharma Monika Swami Ritu Singh Nighat Fahmi R. V. Singh |
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Affiliation: | Department of Chemistry , University of Rajasthan , Jaipur, India |
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Abstract: | The synthetic, spectroscopic, and biological studies of some new palladium(II) and platinum(II) complexes derived from biologically active sulfur donor ligands 1H-indol-2,3-dione benzothiazoline (Bzt 1 H) and 5-nitro-1H-indol-2,3-dione benzothiazoline (Bzt 2 H) have been described. The reactions were carried out in 1:2 molar ratios. The authenticity of the benzothiazolines and their complexes has been established on the basis of elemental analyses; molecular weight determinations; and IR, 1 H NMR, 13 C NMR, and UV spectral studies. Based on IR and 1 H NMR spectral studies, a square-planar structure has been assigned to these complexes. Studies were conducted to assess the comparative growth inhibiting potential of the synthesized complexes against the benzothiazolines for a variety of fungal and bacterial strains. The studies demonstrate that the ligands and complexes possess antimicrobial properties. Further, it was noted that the growth-inhibiting potential of the complexes is greater than the parent benzothiazolines. |
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Keywords: | Antimicrobial activity benzothiazolines Pd(II) and Pt(II) complexes spectral studies |
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