Selenium-Containing Heterocycles: Synthetic Investigation of 3-Amino-2-Ethylselenopyridine Carboxylate Using Sodium Borohydride |
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Authors: | Sh. H. Abdel-Hafez Sh. A. Abdel-Mohsen Y. A. El-Ossaily |
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Affiliation: | Chemistry Department , Assiut University , Assiut , Egypt |
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Abstract: | 3-amino-4,6-dimethyl-2-ethylseleno[2,3-b]pyridine carboxylate (5) was prepared by a reaction of dipyridyl diselenide derivative (3) with sodium borohydride as a reducing agent followed by α-haloester. The reaction of 5 with hydrazine hydrate afforded the corresponding carbohydrazide 8. The benzylidene derivative 9 provided novel heterocycles of pyrimidoseleno pyridine and thiazinoseleno pyridine derivatives (10–12), upon treatment with triethylorthoformate, acetic anhydride, and carbon disulfide, respectively. |
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Keywords: | Dipyridyl diselenide pyrimidoseleno pyridine seleno[2,3-b]pyridine thiazinoseleno pyridine |
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