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Convenient and Highly Efficient Inversion of 1β-OH Configuration of trans-Vitamin D3
作者姓名:Yong  Bin  HAN  Jin  Ping  CHEN  Ying  Ying  LI  Bai  Ning  LIU  Guo  Qiang  YANG  Yi  LI
作者单位:[1]Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100101 [2]Key Laboratory of Photochemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080 [3]Graduate School, Chinese Academy of Sciences, Beijing 100039
基金项目:We are greatly grateful to the Major State Basic Research Development Program, Grant No. F2000078100, the National Natural Science Foundation of China (No.20172059) and Chinese Academy of Sciences.
摘    要:A convenient and highly efficient conversion of 1β-OH-trans-vitamin D3, a main byproduct in synthesis of active vitamin D3, to 1α-OH-trans-vitamin D3 is reported. The conversion could be accomplished in 1 minute with 90% yield.

关 键 词:维他命  维生素  生物活性  合成方法  反应条件
收稿时间:2005-01-31
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