Organocatalytic Hydrophosphonylation Reaction of Carbonyl Groups |
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| Authors: | Dr. Raquel P. Herrera |
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| Affiliation: | Laboratorio de Organocatálisis Asimétrica. Departamento de Química Orgánica, Instituto de Síntesis Química y Catálisis Homogénea (ISQCH) CSIC-, Universidad de Zaragoza, C/ Pedro Cerbuna N°12, Zaragoza, Spain |
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| Abstract: | This revision is covering the limited examples reported for a pivotal strategy in the formation of C?P bonds such as the asymmetric organocatalytic hydrophosphonylation of carbonyl groups (Pudovik reaction). The scope and limitations, and the proposed mechanisms for the scarce different possibilities of asymmetric induction are also shown. The recent evolution and future trends of this undeveloped approach are commented. |
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| Keywords: | asymmetry hydrophosphonylation α -hydroxy phosphonates organocatalysis phosphite Pudovik |
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