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Facile Syntheses of (6S)-6-Fluoroshikimic Acid and (6R)-6-Hydroxyshikimic Acid
Authors:Chuanjun Song  Shende Jiang  Gurdial Singh
Institution:1. Department of Chemistry, University of Sunderland, Sunderland, SR1 3SD, UK;
2. Department of Applied Chemistry, Tianjin University, Tianjin 300072, P. R. China
Abstract:S)-6-Fluoroshikimic acid 2 and (6 R ) 6 hydroxyshikimic acid 3 have been synthesized via an OsO 4 catalysed dihydroxylation of diene 7, which was derived from (-) shikimic acid 1.
Keywords:Shikimate pathway  Shikimic acid  Fluoroshikimic acid  Dihydroxylation  Fluorination
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