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Facile Syntheses of (6S)-6-Fluoroshikimic Acid and (6R)-6-Hydroxyshikimic Acid |
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| Authors: | Chuanjun Song Shende Jiang Gurdial Singh |
| Institution: | 1. Department of Chemistry, University of Sunderland, Sunderland, SR1 3SD, UK; 2. Department of Applied Chemistry, Tianjin University, Tianjin 300072, P. R. China |
| Abstract: | S)-6-Fluoroshikimic acid 2 and (6 R ) 6 hydroxyshikimic acid 3 have been synthesized via an OsO 4 catalysed dihydroxylation of diene 7, which was derived from (-) shikimic acid 1. |
| Keywords: | Shikimate pathway Shikimic acid Fluoroshikimic acid Dihydroxylation Fluorination |
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