3-Benzoyl-2-hydroxy-9-methylpyrido[1,2-A] pyrimidin-4-one |
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Authors: | Harry L Yale |
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Abstract: | The single aberrant product of the reaction between 2-amino-3-methylpyridine ( 2 ) and ethyl benzoylacetate ( 4 ) in diethylbenzene at ca. 180° was 3-benzoyl-2-hydroxy-9-methylpyrido-1,2-a]pyrimidin-4-one ( 5 ). When administered to naive rats, 5 induced behavioral effects strikingly similar to those manifested by morphine-addicted rats who have been deprived of that analgetic. |
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