Oxyresveratrol protects against DNA damage induced by photosensitized riboflavin |
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| Authors: | Chatsumpun Manussanunt Chuanasa Taksina Sritularak Boonchoo Likhitwitayawuid Kittisak |
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| Institution: | Department of Phamacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand. |
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| Abstract: | Riboflavin can be photosensitized to produce reactive oxygen species. In the present study, a DNA damage assay was developed based on the photo reaction of riboflavin. In this test system, oxyresveratrol showed higher DNA protective effect than the well-known antioxidants Trolox and ascorbic acid. The results suggest potential applications for oxyresveratrol as an anti-aging agent and a riboflavin stabilizer. |
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