Reactions of tert-butyl N,N-diethyl-N′-(4-phenylthiazol-2-yl)-phosphorodiamidite with electrophilic reagents |
| |
Authors: | L K Sal’keeva M T Nurmaganbetova E V Minaeva B Z Kokzhalova |
| |
Institution: | (1) Buketov Karaganda State University, ul. Universitetskaya 28, Karaganda, 100026, Kazakhstan |
| |
Abstract: | Previously unknown amidophosphorous acid derivatives were prepared by transamidation of tert-butyl N,N-diethyl-N′-(4-phenylthiazolyl)phosphorodiamidite with 2-amino-4-phenylthiazole, and their reactions with acetyl and benzoyl chloride were studied. These reactions are shown to proceed regioselectively according to the Arbuzov scheme to give the corresponding ketophosphonates. The reaction of the phosphorodiamidite with acetyl chloride in a 1:2 molar ratio involves formation of acetophosphonate that reacts in the enol form to give the corresponding (1-acetoxy)vinylphosphonate. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|