Lack of effect of continuous wave ultrasound exposure on in vivo Chinese hamster cheek pouch epithelial mitotic index |
| |
Authors: | M W Miller C C Church C Cox |
| |
Affiliation: | Department of Biophysics, University of Rochester, School of Medicine and Dentistry, NY 14642. |
| |
Abstract: | Chinese hamster cheek pouches were everted and the epithelia exposed in vivo for 1 min to continuous wave 1.07 MHz ultrasound at intensities ranging from 0.5 to 10.0 W cm-2. Since the mitotic index of the hamster epithelium exhibited a circadian rhythm, the times of sonication and tissue sampling were arranged to allow for detection of a division delay as evidenced by a change in mitotic index in cells insonated in the early S or late S/early G2 phases of the cell cycle. There was no demonstrated effect of the ultrasound exposures on mitotic index. |
| |
Keywords: | |
|
|