Free radical scavenging phenylethanoid glycosides from Leucas indica Linn |
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Authors: | Mostafa M Nahar Nilufar Mosihuzzaman M Makhmoor Talat Choudhary M Iqbal Rahman Atta-Ur |
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Affiliation: | Chemical Research Division, BCSIR Laboratories, Dhaka 1205, Bangladesh. mostafabcsir@yahoo.com |
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Abstract: | A new phenylethanoid glycoside, 2-(3,4-dihydroxyphenyl)-ethyl-O-alpha-L-rhamnopyranosyl-(1 --> 3)-O-alpha-L-rhamnopyranosyl-(1 --> 6)-4-O-E-feruloyl-beta-D-glucopyranoside (3-O-methyl poliu-moside, 1) along with five known phenylethanoid glycosides (2-6) were isolated from the aerial parts of Leucas indica Linn. The structure of compound 1 has been elucidated on the basis of spectral data. Compounds 1-6 exhibited significant antioxidant activity in 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical assay method. These compounds were also found to be moderate inhibitors of xanthine oxidase (XO) enzyme. |
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