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Geometry of the Space of Phylogenetic Trees
Authors:Louis J Billera  Susan P Holmes  Karen Vogtmann
Institution:a Department of Mathematics, Malott Hall, Cornell University, Ithaca, New York, 14853;b INRA, Montpellier, France;Department of Statistics, Stanford University, Stanford, California, 94305, f1
Abstract:We consider a continuous space which models the set of all phylogenetic trees having a fixed set of leaves. This space has a natural metric of nonpositive curvature, giving a way of measuring distance between phylogenetic trees and providing some procedures for averaging or combining several trees whose leaves are identical. This geometry also shows which trees appear within a fixed distance of a given tree and enables construction of convex hulls of a set of trees. This geometric model of tree space provides a setting in which questions that have been posed by biologists and statisticians over the last decade can be approached in a systematic fashion. For example, it provides a justification for disregarding portions of a collection of trees that agree, thus simplifying the space in which comparisons are to be made.
Keywords:phylogenetic trees  semi-labeled trees  associahedron  CAT(0) space  consensus  bootstrap
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