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The concept of template-based de novo design from drug-derived molecular fragments and its application to TAR RNA |
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| Authors: | Andreas Schüller Marcel Suhartono Uli Fechner Yusuf Tanrikulu Sven Breitung Ute Scheffer Michael W. Göbel Gisbert Schneider |
| Affiliation: | (1) Institute of Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-University, Max-von-Laue-Straβe 7, Chair for Chem- and Bioinformatics Siesmayerstr. 70, 60323 Frankfurt am Main, Germany |
| Abstract: | |
| Keywords: | Drug design Evolutionary algorithm RNA ligand Scaffold hopping Virtual screening |
| 本文献已被 PubMed SpringerLink 等数据库收录！ | |