Arylamides of substituted thiocarboxylic acids

Cyclization of arylamides of acetylthioacetic acid with-bromoacetophenone gives mixtures containing hydrobromides of 2-(acetylmethylene)-3, 4-diarylthiazolines and 2-(acetylmethylene)-3, 4-diarylthiazolines, and from these mixtures hitherto undescribed substituted 4-thiazoline derivatives were isolated by chromatography. 2-(Acetylmethylene)-3-aryl-4-thiazolidones were obtained for the first time by reacting arylamides with acetylthioacetic acid with monochloroacetic acid in the presence of fused sodium acetate in glacial acetic acid.