Physicochemical characterization of the endotoxins from Coxiella burnetii strain Priscilla in relation to their bioactivities |
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| Authors: | Toman Rudolf Garidel Patrick Andrä Jörg Slaba Katarina Hussein Ahmed Koch Michel HJ Brandenburg Klaus |
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| Affiliation: | 1.Integrative Biosciences, Oregon Health & Science University, Portland, Oregon, 97239-3097, USA
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| Abstract: | Background Coxiella burnetiiis the etiological agent of Q fever found worldwide. The microorganism has like other Gram-negative bacteria a lipopolysaccharide (LPS, endotoxin) in its outer membrane, which is important for the pathogenicity of the bacteria. In order to understand the biological activity of LPS, a detailed physico-chemical analysis of LPS is of utmost importace. |
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