原子吸收光谱法测定脑血管病患者脑脊液中微量元素

采用原子吸收光谱法对脑梗塞脑出血患者和正常人脑脊液不经消化，直接测定了微量元素Zn，Cu，Fe，Cd含量。该方法的加标回收率为97.6%～104.8%，相对标准偏差(RSD)小于5%。患者脑脊液中Cu含量较正常人低，Zn，Fe，Cd的含量均比正常人明显升高。该测定结果为研究其微量元素含量与脑血管疾病的相关关系以及该疾病的诊断、治疗和预防提供了有用的数据。

Determination of Trace Elements in Cerebrospinal Fluid(CSF) of Patients Suffering Cerebrovascular Disease by Atomic Absorption Spectrometry

The contents of some trace elements such as zinc,copper,iron and cadmium in cerebrospinal fluid(CSF) of normal persons and the patients who suffered cerebral hemorrhage or infarction were determined directly by atomic absorption spectrometry.The method is simple and convenient with a recovery ratio by standard addition being 97.6% to 104.8%,and a relative standard deviation(RSD) is lower than 5%.The test showed that except for the content copper lower than normal,the patients suffering cerebrovascular disease have much higher contents of zinc,iron and cadmium.The result provides useful data for studying the relation between the contents of these trace elements and cerebrovascular disease,as well as diagnosing,treating and preventing this disease.