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First example of an Ugi type reaction on phenylsulfinimine-avermectin B1 derivatives
Authors:Emmanuel Callens
Institution:Syngenta Crop Protection AG, CH-4002 Basel, Switzerland
Abstract:A short synthesis of 4″-(S)-4″-deoxy-4″-trifluoroacetylamino-4″-alkylcarbamoyl-avermectin B14 has been developed through the diastereoselective Ugi reaction to an phenylsulfinimide intermediate.
Keywords:Avermectin  Ugi reaction
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