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Acid-induced conformational switching of aromatic N-methyl-N-(2-pyridyl)amides |
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| Authors: | Iwao Okamoto Mayumi Nabeta Akio Nakashima Tetsuya Takeya Isao Azumaya |
| Institution: | a Showa Pharmaceutical University, 3-3165 Higashi-Tamagawagakuen, Machida, Tokyo 194-8543, Japan b Faculty of Pharmaceutical Sciences at Kagawa Campus, Tokushima Bunri University, 1314-1 Shido, Sanuki, Kagawa 769-2193, Japan |
| Abstract: | Aromatic N-methyl amides containing N-(2-pyridyl) and 2-pyridinecarboxamide or 2,6-pyridinedicarboxamide moieties switch their conformation from cis to trans depending upon the addition of acid. |
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