Transfer allyl esters to thioesters in solid phase condition: synthesis of peptide thioesters by Fmoc chemistry |
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Authors: | Lei Li |
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Affiliation: | School of Pharmaceutical Science, Shandong University, Jinan 250012, PR China |
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Abstract: | A method to transfer allyl esters to thioesters under a solid phase condition has been developed to synthesize peptide thioesters. A Fmoc chemistry has been applied to synthesize the peptide allyl esters, which are selectively transferred to the expected peptide thioesters under solid phase synthesis conditions successfully. |
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Keywords: | Peptide allyl ester Peptide thioester Fmoc solid phase peptide synthesis |
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